Yours, Lord, is the greatness and the power and the glory and the majesty and the splendor, for everything in heaven and earth is yours. Yours, Lord, is the kingdom; you are exalted as head over all. 1 Chronicles 29:11 Barbara JacobyBarbara Jacoby is an award winning blogger that has contributed her writings to multiple online publications that have touched …
Turning the tables on chemotherapy resistance: LIG1 loss exposes a therapeutic vulnerability in triple-negative breast cancer
By: Molly Chiu From: bcm.edu Loss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53 mutations confers resistance to chemotherapy, but researchers at Baylor College of Medicine and collaborating institutions have identified a vulnerability in these cells and used it to their advantage. The team identified underlying molecular mechanisms of platinum resistance …
Turning the tables on chemotherapy resistance: LIG1 loss exposes a therapeutic vulnerability in triple-negative breast cancer
By: Molly Chiu From: bcm.ed oss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53 mutations confers resistance to chemotherapy, but researchers at Baylor College of Medicine and collaborating institutions have identified a vulnerability in these cells and used it to their advantage. The team identified underlying molecular mechanisms of platinum resistance …
Estrogen Receptor (ER) Positive Breast Cancer
From: healthline.com Key Takeaways ER-positive breast cancer means cancer cells have estrogen receptors that promote tumor growth when bound to estrogen. It is the most common type of breast cancer. Treatment for ER-positive breast cancer often involves hormone therapy to block estrogen from activating cancer cell growth, and depending on the stage, may also include surgery and chemotherapy. The outlook …
Living with Breast Cancer: Understanding the Physical and Mental Changes
From : healthline.com Key Takeaways Breast cancer treatments can cause menstrual changes, hair loss, swelling, skin changes, and weight gain, but many of these side effects are temporary and manageable with proper care. Mental health support, such as therapy and self-care practices, is crucial during breast cancer treatment due to the common occurrence of depression and anxiety. Strategies can help …
Why Not to Recommend Products and Services as a Breast Cancer Patient
View PostFDA Approves Gedatolisib Plus Fulvestrant ± Palbociclib for Hormone Receptor–Positive, HER2-Negative, Locally Advanced/Metastatic Breast Cancer
By: Ashling Wahner From: onclive.com Key Takeaways Indication targets endocrine-pretreated metastatic HR-positive/HER2-negative disease specifically without PIK3CA mutations, positioning therapy for patients ineligible for PI3Kα-mutant–directed strategies. Triplet therapy with gedatolisib/fulvestrant/palbociclib produced median PFS 9.3 months versus 2.0 months with fulvestrant alone, yielding an adjusted hazard ratio of 0.24. Doublet gedatolisib plus fulvestrant demonstrated median PFS 7.4 months and significant risk reduction …
Flavonoid-rich foods may blunt breast cancer risk tied to genetics
By: Tarun Sai Lomte From: news-medical.net A large prospective study links tea, apples, oranges, berries, and other flavonoid-rich foods with reduced breast cancer risk, including among women with elevated genetic susceptibility. In a recent ‘Article in Press’ study published in the journal npj Breast Cancer, researchers assessed the association between the flavodiet score (FDS), a measure of flavonoid-rich food intake, and …
Travel Tips for Metastatic Breast Cancer
By: Ashley Welch From: everydayhealth.com While traveling with metastatic breast cancer safely and confidently is completely possible, it involves a bit of planning. Before you set off on your journey, check with your care team for the all-clear. “Before traveling, a patient with breast cancer should first consult their doctor to confirm if it is safe to travel, considering their …
Never again will they …
‘Never again will they hunger; never again will they thirst. The sun will not beat down on them,’ nor any scorching heat. For the Lamb at the center of the throne will be their shepherd; ‘he will lead them to springs of living water.’ ‘And God will wipe away every tear from their eyes.’ Revelation 7:16-17 Barbara JacobyBarbara Jacoby is …