By: Hannah Murphy From: healthimaging.com Example of the four types of breast tissue density. The density of fibroglandular tissue inside the breast impacts the ability to easily see cancers. On X-ray mammography, cancer and dense breast tissue both appear as white and can hide smaller cancers on 2D mammography. Dense breasts are also a risk factor for cancer. Cancers are …
How Does Breast Cancer Spread or Metastasize?
From: healthline.com Breast cancer can spread through your lymph circulatory system to your lymph nodes. In later stages, it can also spread to other organs, like your brain or lungs. When breast cancer spreads to other sites in the body, doctors call this “metastasizing.” There are several ways cancer can spread in the body. Breast cancer can spread lymphatically from …
Cancer-Like Genetic Mutations Found in Healthy Breast Tissue Cells
From: insideprecisionmedicine.com Researchers at the University of British Columbia (UBC), BC Cancer, Harvard Medical School, and Memorial Sloan Kettering Cancer Center (MSK) have identified early genetic alterations in healthy women’s breast cells that could be among the first steps leading to breast cancer. The findings, published today in Nature Genetics, suggest that cancer-like mutations appear silently in breast cells that …
Novel CAR T-cell therapy demonstrates efficacy and safety in preclinical models of HER2-positive solid tumors
By: Vall d’Hebron Institute of Oncology From: medicalxpress.com One-third of HER2-positive (HER2+) tumors express the P95HER2 protein, which associates with an aggressive form of breast cancer with a poorer prognosis. Investigators of the Vall d’Hebron Institute of Oncology’s (VHIO) Growth Factors Group, in collaboration with researchers of the Cancer Research Program of Hospital del Mar Research Institute (HMRI), Barcelona, have …
The Spirit of Christmas from a Breast Cancer Survivor
View PostData Continue to Help Shape CDK4/6 Inhibitor Selection, Sequencing in HR+ Breast Cancer
By: Ryan Scott From: onclive.com Robust phase 3 trial data have led to the integration of CDK4/6 inhibitors into the hormone receptor–positive, HER2-negative breast cancer treatment paradigm, and the continued emergence of data have helped answer selection and sequencing questions about agents such as ribociclib (Kisqali), abemaciclib (Verzenio), and palbociclib (Ibrance), according to Lubna Naaz Chaudhary, MD, MS. “In our …
People with breast cancer often have unmet emotional, financial needs
By: Jennifer Byrne From: healio.com Many women with breast cancer struggle with unmet emotional or financial needs, according to research presented at American College of Surgeons Clinical Congress. These challenges — revealed during an analysis of posts on the social media platform Reddit — persist during treatment and well into survivorship, findings of two poster presentations showed. A research team …
Photoacoustic imaging technique reduces skin tone bias in breast cancer detection
By: SPIE From: medicalxpress.com Breast cancer is a major health concern worldwide, and early detection is crucial for effective treatment. Traditional imaging methods, such as mammography, have limitations, especially for women with dense breast tissue. Photoacoustic imaging, which combines light and sound to create detailed images of breast tissue, offers a promising alternative. However, recent research has highlighted a significant …
IBI354 Shows Efficacy and Safety in HER2+ and HER2-Low Advanced Breast Cancer
Author: Jax DiEugenio From: onclive.com Key Takeaways IBI354 demonstrated significant efficacy in HER2-positive and HER2-low breast cancer, with ORRs of 67.8% and 41.8%, respectively. The phase 1 study included dose-escalation and dose-expansion phases, with no dose-limiting toxicities observed up to 18 mg/kg. The safety profile of IBI354 was favorable, with mild treatment-related adverse effects, including nausea and decreased blood cell …
Thyroid Dysfunction is Common in Women With Breast Cancer Following Radiation Therapy
By: Rob Dillard From: docwirenews.com Thyroid and parathyroid dysfunction is common among women with breast cancer (BC) following radiotherapy (RT), according to a study published in the Canadian Oncology Nursing Journal. “The current advances in (RT) have improved the outcome of breast cancer (BC) patients. Despite its therapeutic benefits, the iatrogenic toxicities of RT and its impact on BC survivors …