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Breast cancer gene mutation clinical trial to take place in Australia

In Clinical Trials by Barbara Jacoby

By: Meagan Dillon and Leah MacLennan From: abc.net.au Breast cancer is a disease that predominantly impacts women, but it is not unheard of for men to also carry a rare genetic mutation that significantly increases the risk. Helen Hicks’s husband Tony Ransom is in that category — but the Adelaide couple will not know if the mutation has been passed …

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Breast cancer risk among BRCA carriers influenced by timing, number of pregnancies

In In The News by Barbara Jacoby

By: Terry MB, et al. JNCI Cancer Spectr. 2018;doi:10.1093/jncics/pky078. From: healio.com The timing and number of full-term pregnancies appeared to influence the risk for breast cancer among women with BRCA1 or BRCA2 mutations, according to study results published in Journal of the National Cancer Institute Cancer Spectrum. BRCA1 carriers who had only one full-term pregnancy and BRCA2 carriers who had …

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Lynparza, First In Its Class Of Cancer Drugs, Offers Surprisingly Broad Activity

In In The News by Barbara Jacoby

By: Elaine Schattner From: forbes.com ..What’s emerging is that this new class of drugs, once considered of limited benefit and primarily for cancer patients with BRCA mutations, offers a wide range of anti-tumor activity. In December 2014, the FDA approved the first medication of this type, olaparib (brand name: Lynparza, AstraZeneca) for treatment of refractory ovarian cancer. The drug comes …