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New Studies Using CELLSEARCH Circulating Tumor Cell Test to be Featured at San Antonio Breast Cancer Symposium

In Clinical Trials by Barbara Jacoby

Research Adds to Growing Evidence of Clinical Utility of CTCs for the management of Metastatic Breast Cancer Patients Menarini Silicon Biosystems announced today that new data utilizing the company’s CELLSEARCH® Circulating Tumor Cell Test will be presented at the upcoming 2018 San Antonio Breast Cancer Symposium (SABCS). A total of 21 studies will be presented: 20 posters and an oral …

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Targeting Innovation in Small Cell Lung Cancer

In Clinical Trials by Barbara Jacoby

By: Heather Stringer From: curetoday.com After consulting multiple doctors about her ongoing cough and congestion, LeeAnn Devore asked one of her physicians if she might have lung cancer. “He said the symptoms weren’t right,” says Devore, 66, of Magnolia, Texas. Three X-rays in five months confirmed that she had pneumonia in her right lung, yet she wasn’t responding to traditional …

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New Clinical Trial for Triple-Negative Breast Cancer at Sylvester Comprehensive Cancer Center

In Clinical Trials by Barbara Jacoby

Vaccine Designed to Prevent Recurrence Panic washed over Jackie Barrett when she first received her breast cancer diagnosis. “My eyes went dark. I couldn’t hear anything. It was like a train was coming at me,” she says. Jackie’s oncologist explained that her type of breast cancer is called triple-negative because it does not have receptors for estrogen, progesterone or the …

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Building Disease Management Teams to Harness Clinical Trial Growth

In Clinical Trials by Barbara Jacoby

By: Mindy Waizer From: oncnursingnews.com The clinical trials program at the Lehigh Valley Cancer Institute (LVCI) grew exponentially in a short period of time. A great problem to have, certainly, but challenging to the organization. To ensure the successful absorption and growth of new trials, two nurses drove an initiative to reorganize LVCI’s framework of their current disease management teams. …

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New insight into why malaria drugs work against some cancers could boost drug development

In Clinical Trials by Barbara Jacoby

By: Arlene Weintraub From: fiercebiotech.com There are currently about 20 clinical trials underway evaluating a class of malaria drugs known as chloroquines in several tumor types, including breast cancer, lung cancer and multiple solid tumors, according to ClinicalTrials.gov. Anti-malarial drugs, in fact, have long been of interest in the oncology community because of their ability to shrink some cancers. But …

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First-in-Human Trial Launched for Super-Enhancer Inhibitor GZ17-6.02

In Clinical Trials by Barbara Jacoby

SOURCE: Translational Drug Development From: apnews.com Genzada Pharmaceuticals USA Inc., a subsidiary of Ionics Life Sciences Limited (Genzada), announced today that the U.S. Food and Drug Administration (FDA) has approved its Investigational New Drug (IND) application for a Phase 1 human clinical trial of the company’s flagship molecule GZ17-6.02 (6.02) for patients with advanced solid organ tumors or lymphoma. “We …

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Experimental Immunotherapy Drug Shows Promise for Non-Hodgkin Lymphoma

In Clinical Trials by Barbara Jacoby

From: everydayhealth.com What’s New A small, early-phase clinical trial testing a new drug combination produced impressive outcomes for patients with relapsed or refractory non-Hodgkin lymphoma, according to a report published November 1, 2018, in the New England Journal of Medicine. Researchers at multiple institutions tested an experimental drug known as 5F9 with the standard cancer drug Rituxan (rituximab) in 22 people. Eleven of the …

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Norwalk Hospital reports positive results with breast cancer clinical trials

In Clinical Trials by Barbara Jacoby

By: Kevin Zimmerman From: westfaironline.com Four cutting-edge breast cancer clinical trials recently launched at Norwalk Hospital’s C. Anthony and Jean Whittingham Cancer Center are giving hope to patients diagnosed with triple negative breast cancer, an aggressive form of the disease that cannot be treated with hormone therapies or other cancer-fighting drugs. “We started about six months ago,” said Dr. Linda …

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Advanced breast cancer patients can benefit from immunotherapy-chemotherapy combination

In Clinical Trials by Barbara Jacoby

Source: upmc.com From: news-medical.net Patients with an aggressive form of advanced breast cancer can benefit from immunotherapy when used in combination with chemotherapy as first-line treatment, according to the results of a large international Phase III clinical trial published today in the New England Journal of Medicine and led by a researcher at the UPMC Hillman Cancer Center and the …

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Immunotherapy trial offers new hope for people with aggressive breast cancer

In Clinical Trials by Barbara Jacoby

Source: qmul.ac.uk From: news-medical.net There is new hope for people with an aggressive type of breast cancer, as an immunotherapy trial shows for the first time that lives can be extended in people with triple-negative breast cancer. New research led by Queen Mary University of London and St Bartholomew’s Hospital has shown that by using a combination of immunotherapy and …