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Why Patients Avoid Clinical Trials

In Clinical Trials by Barbara Jacoby

By: Cynthia Verst, PH.D., President, Design and Delivery Innovation R&D Development Solutions, IQVIA From: pharmavoice.com And how big data, analytics, technology and domain expertise can help change the paradigm The pharma industry has a big challenge when it comes to clinical trials, one that continues to hinder the industry’s approach to research. Sponsors want patients to enroll in their trials, …

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Dynamic duo in Pinehurst appreciates opportunity to participate in clinical trial

In Clinical Trials by Barbara Jacoby

From: sandhillssentinel.com While FirstHealth of the Carolinas has earned widespread acclaim as a national leader in community health, Sandhills residents may not know of a superpower within the system that offers opportunities for patients in the region and worldwide: its extensive clinical trials program. “FirstHealth offers a wide array of clinical trials that far exceeds the average for regional medical …

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High Marks for Proton-Beam RT in Breast Cancer

In Clinical Trials by Barbara Jacoby

By: Charles Bankhead From: medpagetoday.com Women with locally advanced breast cancer requiring regional lymph node irradiation had similar disease control with less toxicity with proton-beam radiation therapy (RT) as compared with historical patients treated with conventional radiotherapy, investigators in a small prospective study reported. The 69 evaluable patients had a 5-year locoregional failure rate of 1.5% and 5-year overall survival …

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NRG Oncology Approves Danbury and Norwalk Hospitals as Primary Sites for Clinical Research

In Clinical Trials by Barbara Jacoby

·         Danbury Hospital and Norwalk Hospital received approval to join NRG Oncology as primary clinical research sites. This means that patients at Danbury Hospital and Norwalk Hospital now have expanded access to the latest clinical trials for breast cancer, radiation oncology, and gynecologic cancer. ·         Through NRG Oncology clinical trials, Danbury Hospital and Norwalk Hospital patients can receive the most …

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Outsourcing in clinical trials: an EU struggle? – Data report analysis

In Clinical Trials by Barbara Jacoby

By: Claudette Hodge From: knect365.com In the collaborative environment of clinical trials, partnerships and outsourcing are essential, yet can open the door to a world of day-to-day challenges. In our recent State of the Industry Report 2019, we investigated what today’s clinical trials professionals see as the most prominent risks faced in managing relationships with third-party organisations. The survey was …

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Oncoceutics Announces FDA Acceptance of Investigational New Drug Application for Phase I Trial of ONC206

In Clinical Trials by Barbara Jacoby

Oncoceutics, Inc. announced that the U.S. Food and Drug Administration (FDA) has accepted the company’s Investigational New Drug (IND) application for ONC206, allowing the first-in-human trial of the compound. ONC206 is the first of the family of drug candidates, which we call “imipridones”, that possess the same core chemical structure as ONC201. The first clinical trial for ONC206 in adults …

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Quest for new cancer treatment crosses milestone

In Clinical Trials by Barbara Jacoby

Source: Rice University From: sciencedaily.com A cancer therapy has crossed a milestone in clinical trials, a major development in a decades-long quest to develop a treatment that destroys tumors without the debilitating side effects of chemotherapy, invasive surgery and radiation. A cancer therapy invented at Rice University has crossed a milestone in clinical trials, a major development in a decadeslong …

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FDA Calls for Men to be Enrolled in Breast Cancer Trials

In Clinical Trials by Barbara Jacoby

By: Michael Mezher From: raps.org The US Food and Drug Administration (FDA) on Monday issued new draft guidance encouraging drugmakers to enroll male patients in breast cancer clinical trials. While men account for less than one percent of breast cancer cases, FDA says they are more likely to be diagnosed at a later stage of disease and have historically been …

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New Strategies Are Evolving for Breast Cancer Brain Metastases

In Clinical Trials by Barbara Jacoby

By: Tony Berberabe, MPH From: onclive.com A greater focus on studying mechanisms for therapies that penetrate the blood–tumor barrier and the expansion of clinical trial eligibility criteria are opening the door for advancements that may help patients with metastatic breast cancer that has spread to the brain, according to Carey K. Anders, MD. Historically, the clinical development of treatments in …

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Another myeloma drug with same target as CAR-Ts shows successful Phase II results

In Clinical Trials by Barbara Jacoby

By: Alaric DeArment From: medcitynews.com Without providing details, GlaxoSmithKline said its trial of BCMA-targeting belantamab mafodotin was positive. The company plans to submit for regulatory approvals later this year – potentially ahead of bluebird and Celgene’s expected filing next year for the CAR-T bb2121. A Phase II study of a GlaxoSmithKline drug to treat the blood cancer multiple myeloma has …