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PrimeVax Immuno-Oncology Signs Exclusive Worldwide Dengue Virus License with US Army for Cancer Treatments

In Clinical Trials by Barbara Jacoby

Source: PrimeVax Immuno-Oncology From: pipelinereview.com Novel Therapy Would Be First in Cancer Patients Using Dengue Virus PrimeVax Immuno-Oncology, Inc. announced today that the company has just signed an exclusive, worldwide license with the US Army Medical Materials Development Activity, Ft. Detrick, MD, USAMMDA, authorizing PrimeVax to use dengue virus-1 #45AZ5 strain for treatment of cancer. “This is an unprecedented move,” …

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Veru Initiates Clinical Trial for Proprietary, Novel, First-in-Class Drug for Advanced Prostate Cancer

In Clinical Trials by Barbara Jacoby

Source: Veru, Inc. From: globenewswire.com Veru Inc. (NASDAQ: VERU), an oncology and urology biopharmaceutical company, today announced that it has initiated and enrolled the first patient in a clinical trial of its proprietary, next generation prostate cancer drug, VERU-111. The open-label Phase 1b/2 clinical trial for VERU-111, a novel oral drug, will be evaluated in men with metastatic refractory prostate …

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TAPUR: When Chemo Stops Working

In Clinical Trials by Barbara Jacoby

From: ksat.com MIAMI, Fla. (Ivanhoe Newswire) – Finding out you have cancer is scary enough. But if the doctor says it’s stage 4 then you know it’s life-threatening. A nationwide study changed the life of one woman who was told she was ready for hospice. Anita Shangvi has battled breast cancer since 2007. Shangvi said, “First recurrence was 2011.” Then three …

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Israeli treatment freezes cancerous tumors, eliminating need for surgery

In Clinical Trials by Barbara Jacoby

By: WKRC From: local12.com CAESAREA, Israel (CBS Newspath/Reuters) – When Nelida Ivaldi was diagnosed with a tumor in her breast, she was terrified of what she thought was going to be a long, painful treatment. But after undergoing cryoablation therapy to freeze her tumor, she was surprised by how quick and painless the whole thing was. Ivaldi, a retired teacher, …

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Alisertib-Based Combo Improves Survival Outcomes in Ovarian, Breast Cancer

In Clinical Trials by Barbara Jacoby

By: Jessica Skarzynski From: curetoday.com For some time now, paclitaxel has been considered standard of care in the treatment of patients with platinum-resistant ovarian cancer; however, recent research has shown the addition of the investigational drug alisertib to a paclitaxel regimen demonstrated promising activity in patients with recurrent ovarian cancer or advanced breast cancer. In the JAMA Oncology study, the …

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Mayo Clinic sees 80% increase in breast cancer clinical trial enrollment with IBM Watson’s clinical trial matching system

In Clinical Trials by Barbara Jacoby

By: Julie Spitzer  From: beckershospitalreview.com Rochester, Minn-based Mayo Clinic enrolled more patients in its breast cancer clinical trials after implementing IBM Watson Health’s Watson for Clinical Trials Matching, a cognitive computing system, according to early results of use in Mayo’s oncology practice. Although clinical trials increase patients’ access to new, promising or emerging treatments, matching and enrolling them in trials …

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Researchers Successfully Turn Breast Cancer Cells Into Fat to Stop Them From Spreading

In Clinical Trials by Barbara Jacoby

By: JACINTA BOWLER From: sciencealert.com Researchers have been able to coax human breast cancer cells to turn into fat cells in a new proof-of-concept study in mice. To achieve this feat, the team exploited a weird pathway that metastasising cancer cells have; their results are just a first step, but it’s a truly promising approach. When you cut your finger, …

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TRIO Enrolls First Patient Into PHASE III NATALEE Clinical Trial

In Clinical Trials by Barbara Jacoby

From: ptcommunity.com Translational Research In Oncology (TRIO), in collaboration with Novartis and under the direction of Dennis Slamon, MD, PhD, TRIO Chairman/Executive Director and Director of Clinical Translational Research at the University of California, Los Angeles Jonsson Comprehensive Cancer Center, announces enrollment of the first patient into its newest clinical trial, NATALEE (New Adjuvant TriAl with LEE). NATALEE is a …

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Research to remove exclusions on immunotherapy

In Clinical Trials by Barbara Jacoby

By: Michael Hardy From: mdanderson.org People used to ask Patrick Hwu, M.D., why he decided to devote his career to melanoma, a skin cancer with high mortality rates and limited treatment options. “They would come up to me and say, ‘How can you treat advanced melanoma? Isn’t that depressing?’ And actually, it was — my clinic of advanced melanoma patients …

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Clinical Trial Saves Life of Stage 4 Kidney Cancer Patient

In Clinical Trials by Barbara Jacoby

By: Bianca Castro From: nbcdfw.com When a well-known journalist in Dallas learned he had stage 4 kidney cancer, he was told he had three, possibly four, years to live. One year, later, the tumor threatening his life is gone and it’s thanks to a clinical trial at UT Southwestern. Robert Wilonsky will tell you there’s nothing special about him. He’ll …