Women with breast cancer who have sufficient vitamin D levels have improved survival outcomes compared to those with vitamin D deficiency, according to research published in the Journal of the National Comprehensive Cancer Network. Patients with sufficient levels of vitamin D also have a lower incidence of cardiometabolic risk factors than those without sufficient levels, study researchers reported. In this …
Left-Side Breast Cancer EBRT Linked to Minimal Long-Term Cardiovascular Risk
By: Mary Ellen Schneider From: cancertherapyadvisor.com External beam radiation therapy (EBRT) for left-sided breast cancer has limited long-term cardiovascular risks, according to results published in JAMA Network Open. The findings suggest that contemporary photon-based EBRT techniques that reduce mean radiation dose to the heart have resulted in lower cardiovascular risks than those historically associated with left-side breast cancer radiation treatment, …
Advancing Immunotherapy in Metastatic Cancers: Identifying Mechanisms, Targeting Sanctuaries
By: Jasenka Piljac Zegarac, PhD From: ascopubs.org Key Points: As the use of immunotherapy for the treatment of metastatic cancers advances, challenges remain in understanding the mechanisms of metastasis and why certain tumors spread to specific distant organs. Oncologists still treat metastatic disease based on the original tumor site, and most treatment guidelines often do not consider the specific site …
Low BMI Linked to Progression in HR+/HER2– Breast Cancer Treated With CDK4/6i
By: Vicki Moore, PhD From: cancertherapyadvisor.com A BMI of below 18.5 was associated with progression compared with a reference BMI range of 18.5 to 25 Low body mass index (BMI) is associated with tumor progression in patients with hormone receptor-positive (HR+)/HER2-negative (HER–) metastatic breast cancer being treated with CDK4/6 inhibitor (CDK4/6i) therapy, according to research presented in a poster at …
International Intel: a Glance at the Top Global Breast Cancer News From January-March 2026
By: Ashling Wahner From: onclive.com Key Takeaways China’s NMPA conditionally approved neoadjuvant T-DXd→THP in stage II/III HER2-positive breast cancer, improving pCR to 67.29% versus 56.25% with dose-dense AC→THP. NMPA authorized sacituzumab tirumotecan for unresectable/metastatic HR+/HER2− disease after endocrine therapy and ≥1 chemotherapy line, with median PFS 8.3 versus 4.1 months. EMA validated a Type II variation for first-line T-DXd plus …
Innate immunity genes may influence earlier breast cancer onset in BRCA1 carriers
Source: BMJ Group From: news-medical.net Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers of the harmful BRCA1 genetic mutation, reveal preliminary findings published online in the Journal of Medical Genetics. The strongest association was found for genes involved in the activation of natural killer cells, which serve …
Latest Breast Cancer Research You Need to Know in 2026
From: breastadvocateapp.com In the ever-evolving world of breast cancer care, recent studies are rewriting what’s possible—from how early cancer is detected to how precisely it’s treated. The newest wave of research isn’t just about survival. It’s about smarter screening, personalized care, and empowering patients with better options. Here’s a closer look at the most impactful developments shaping breast cancer care in …
Analysis Links Radioactive Iodine Therapy to Breast Cancer Risk
By: Kerry Dooley Young From: medscape.com Radioactive iodine (RAI) treatment for hyperthyroidism was associated with an increased incidence of breast cancer but not with an overall increase in cancer incidence or mortality, a new study found. Researchers analyzed data from the University of Michigan’s de-identified database, examining cancer diagnoses among patients treated for hyperthyroidism between January 1, 2006, and December …
Aging reshapes breast tissue creating environment favorable for cancer
Source: University of Cambridge From: news-medical.net Scientists have created the most detailed map to date, comprised of over 3 million cells, showing how breast tissue changes as women age – including dramatic changes during menopause. The map reveals how, as women age, the number of cells in their breast tissue decreases, and these in turn proliferate less, and the structure …
Understanding Breast Cancer Tumor Size Staging
From: healthline.com Key takeaways Breast cancer staging uses tumor size and location, plus spread to lymph nodes and other organs, to show how advanced the cancer is. Doctors describe tumor size using the TNM System “T” categories, from T1 (less than 2 centimeters) to T4 (when it invades the chest wall or skin). Tumor size and staging help guide treatment …