From: breastcancerapp.com
A new study suggests that women who choose DIEP flap breast reconstruction may experience better quality of life within just five months after surgery.
Researchers examined how different breast surgery options affected women after breast cancer treatment. They compared mastectomy alone, implant reconstruction, and autologous reconstruction using DIEP or FCI flaps.
The study is part of the REKO 001 trial, a long-term research project that will follow patients for 10 years.
Why Quality of Life Matters
Breast cancer survival rates continue to improve. As a result, doctors are paying more attention to quality of life after treatment.
Many women who need a mastectomy choose breast reconstruction. However, there is limited long-term data comparing different reconstruction methods.
The REKO 001 trial aims to help patients and surgeons make more informed decisions.
About the Study
Researchers enrolled 227 women between 2017 and 2022.
Participants were divided into three groups:
- 74 women had a mastectomy without reconstruction.
- 77 women received implant-based reconstruction.
- 76 women underwent DIEP or FCI flap reconstruction.
Patients completed quality-of-life surveys before surgery and again five months later.
Researchers also tracked complications that required hospitalization or additional surgery.
DIEP Patients Reported the Biggest Improvements
Women in the DIEP/FCI group started with the lowest quality-of-life scores before surgery.
Despite that, they were the only group to show significant improvements across several quality-of-life categories after five months.
Improvements included:
- Better psychosocial well-being
- Higher satisfaction with their breasts
- Improved overall quality of life scores
Researchers believe these findings highlight the emotional and psychological benefits of autologous reconstruction.
Implant Reconstruction Showed Strong Results
Women with implant reconstruction had the highest quality-of-life scores before surgery.
Five months later, they continued to score higher than women who had mastectomy alone.
The implant group also experienced an improvement in emotional well-being.
Overall, implant reconstruction produced better quality-of-life outcomes than mastectomy without reconstruction.
Mastectomy Alone Had Lower Scores
Women who underwent mastectomy without reconstruction generally reported lower quality-of-life scores.
Several areas declined during the first five months after surgery.
Researchers noted that many women in this group were still receiving treatments such as chemotherapy or radiation during follow-up. This may have affected their results.
Higher Complication Rates With DIEP Reconstruction
While DIEP reconstruction showed the greatest quality-of-life improvements, it also carried the highest risk of complications.
Complication rates within five months were:
- Mastectomy: 4.1%
- Implant reconstruction: 11.7%
- DIEP/FCI reconstruction: 17.1%
Some complications required additional surgery or hospital stays.
Researchers say patients should carefully weigh these risks when choosing a reconstruction method.
Other Factors That Affected Quality of Life
The study identified two additional factors linked to lower quality of life:
Higher Body Mass Index (BMI)
Women with higher BMI scores generally reported lower quality-of-life outcomes across several categories.
Radiation Therapy
Radiation treatment was associated with lower physical, emotional, and sexual well-being scores.
These findings suggest that overall health and cancer treatments can influence recovery after surgery.
What This Means for Breast Cancer Patients
The study provides valuable information for women considering breast reconstruction.
DIEP flap reconstruction may offer meaningful improvements in quality of life within a relatively short period.
However, the procedure is more complex and comes with a greater risk of complications.
Implant reconstruction also produced positive results and outperformed mastectomy alone in several areas.
Researchers will continue following participants for 2, 5, 7, and 10 years. Future results will reveal whether these early benefits continue over time.
Key Takeaway
Women who underwent DIEP flap reconstruction experienced the most improvement in quality of life during the first five months after surgery. However, they also faced the highest complication rates. Both DIEP and implant reconstruction generally resulted in better quality-of-life outcomes than mastectomy alone.
At Breast Advocate, we believe that understanding the latest research empowers patients to make informed choices about their care. As breakthroughs like this continue to evolve, patients and clinicians alike gain more options for treatment options that protect both health and quality of life.
Barbara Jacoby is an award winning blogger that has contributed her writings to multiple online publications that have touched readers worldwide.

