“May this be a season of listening, alignment, and prosperity. May you always keep an open heart and move with intention.” – Dhayana Alejandrina Barbara JacobyBarbara Jacoby is an award winning blogger that has contributed her writings to multiple online publications that have touched readers worldwide. LetLifeHappen.com
Advancing Immunotherapy in Metastatic Cancers: Identifying Mechanisms, Targeting Sanctuaries
By: Jasenka Piljac Zegarac, PhD From: ascopubs.org Key Points: As the use of immunotherapy for the treatment of metastatic cancers advances, challenges remain in understanding the mechanisms of metastasis and why certain tumors spread to specific distant organs. Oncologists still treat metastatic disease based on the original tumor site, and most treatment guidelines often do not consider the specific site …
Life is beautiful and unpredictable. So make sure …
“Life is beautiful and unpredictable. So make sure that you wake up being grateful for the air you breathe, the people who make you feel safe and seen, the memories made, the goals accomplished, the answered prayers, the smiles shared, and the love given: be grateful for it all.” – Dhayana Alejandrina Barbara JacobyBarbara Jacoby is an award winning blogger …
Low BMI Linked to Progression in HR+/HER2– Breast Cancer Treated With CDK4/6i
By: Vicki Moore, PhD From: cancertherapyadvisor.com A BMI of below 18.5 was associated with progression compared with a reference BMI range of 18.5 to 25 Low body mass index (BMI) is associated with tumor progression in patients with hormone receptor-positive (HR+)/HER2-negative (HER–) metastatic breast cancer being treated with CDK4/6 inhibitor (CDK4/6i) therapy, according to research presented in a poster at …
The Mammogram Discussions for Breast Cancer Continue
View PostYou can lock a songbird but you can’t lock …
“You can lock a songbird but you can’t lock the song. You may confine it but the more you confine it, the more it will sing the sadness, giving it to the winds. After all, caged birds sing some of the most beautiful songs.” -Jayita Bhattacharjee Barbara JacobyBarbara Jacoby is an award winning blogger that has contributed her writings to …
International Intel: a Glance at the Top Global Breast Cancer News From January-March 2026
By: Ashling Wahner From: onclive.com Key Takeaways China’s NMPA conditionally approved neoadjuvant T-DXd→THP in stage II/III HER2-positive breast cancer, improving pCR to 67.29% versus 56.25% with dose-dense AC→THP. NMPA authorized sacituzumab tirumotecan for unresectable/metastatic HR+/HER2− disease after endocrine therapy and ≥1 chemotherapy line, with median PFS 8.3 versus 4.1 months. EMA validated a Type II variation for first-line T-DXd plus …
Go after what you want in …
“Go after what you want in life. Don’t just talk about it. Take a step, run.” – Bhuwan Thapaliya Barbara JacobyBarbara Jacoby is an award winning blogger that has contributed her writings to multiple online publications that have touched readers worldwide. LetLifeHappen.com
Innate immunity genes may influence earlier breast cancer onset in BRCA1 carriers
Source: BMJ Group From: news-medical.net Damaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers of the harmful BRCA1 genetic mutation, reveal preliminary findings published online in the Journal of Medical Genetics. The strongest association was found for genes involved in the activation of natural killer cells, which serve …
There is always something new, something
“There is always something new, something unexpected, on a distant horizon, and life forever changes. It twists and turns in ways one could never predict.” – Juniper Lake Fitzgerald, Apotheosis Barbara JacobyBarbara Jacoby is an award winning blogger that has contributed her writings to multiple online publications that have touched readers worldwide. LetLifeHappen.com